The response to double-dose hepatitis B vaccination in patients with HIV
نویسندگان
چکیده
Objectives: Prevention of hepatitis B virus (HBV) infection is necessary for patients with human immunodeficiency (HIV), since co-infection associated increased in mortality. The aim this study was to investigate response double-dose HBV vaccine HIV. Methods: A total 149 HIV were retrospectively evaluated. Sixty-eight who seronegative and administered included the study. According anti HBs levels, evaluated three groups: < 10 mIU/mL, 10-100 mIU/mL ≥ 100 mIU/mL. Age, sex, transmission route, smoking, alcohol-substance abuse, comorbidities, CD4+ T cells counts viral load compared groups. Results: rate vaccination (anti mIU/mL) 69.1%. Age statistically significantly higher group than >100 group. level lower a cell count 200 cells/μL (< mIU/mL). Conclusions: use high-dose necessity as well revaccination improve immunogenicity In our study, low lymphocyte older age found have negative effect on response.
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ژورنال
عنوان ژورنال: The European Research Journal
سال: 2022
ISSN: ['2149-3189']
DOI: https://doi.org/10.18621/eurj.822127